Multiple mechanisms of action

• Anti-inflammatory – suppresses the synergistic action of these immune cells and blocks immune responses.
• Immunomodulatory – dynamic regulation of informational molecules.
• Anti-itch – Impacts the sensory afferent nerves, disrupting the itch-scratch cycle.
• Repairing – rapidly repair keratinocytes.

Broad cytokine coverage for immuno-inflammatory skin diseases

Our clinical trial demonstrates that BHLA-18 regulates Th1/Th2 balance, and decreases the production of pro-inflammatory cytokines TSLP, IL-4, IL-6, IL-10, IL-12, IL-33, TNF-α.

Restoring skin barrier function

BHLA-18 restoring skin barrier function, enhancing antimicrobial peptide production, restoring keratinocyte differentiation, and suppressing itching symptoms.

BHLA-18 is designed to suppress inflammatory pathways in the epidermis layer

Dendritic and Langerhans cells in the skin sense these environmental factors and release cytokines , BHLA-18 is targeting and suppressing inflammatory in the front line to avoid systemic absorb.

Promote collagen synthesis

Collagen is a crucial element of the skin, directly related to skin structure integrity and wound repair. BHLA-18 can promote collagen synthesis, aiding in wound hemostasis and enhancing skin wound repair.

Potential in many skin diseases

BHLA-18 has the potential in many skin diseases including

• Atopic Dermatit
• Psoriasis
• Acne
• Xerosis cutis